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Self-amplifying mRNA vaccines appear safe in lab and animal tests

mRNA vaccines contain instruction codes for making parts of pathogenic viruses. Can so-called self-amplifying types of such vaccines form unwanted and dangerous connections with other viruses? Yes, say Wageningen virologists ...

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How a bacterium supports healing of chronic diabetic wounds

There are many important reasons for keeping cuts and sores clean, but new research from the Perelman School of Medicine at the University of Pennsylvania shows that a certain bacterium, Alcaligenes faecalis (A. faecalis), ...

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New protein discovery may influence future cancer treatment

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of ...

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Study debunks link between moderate drinking and longer life

Probably everyone has heard the conventional wisdom that a glass of wine a day is good for you—or you've heard some variation of it. The problem is that it's based on flawed scientific research, according to a new report ...

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Guideline on management of central airway obstruction released

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on central airway obstruction (CAO). Published in the journal CHEST, the guideline contains 12 evidence-based recommendations to ...

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Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

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Researchers develop painless tattoos that can be self-administered

Instead of sitting in a tattoo chair for hours enduring painful punctures, imagine getting tattooed by a skin patch containing microscopic needles. Researchers at the Georgia Institute of Technology have developed low-cost, ...

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Can the brain recover after boxers and MMA fighters stop fighting?

Boxers and mixed martial arts (MMA) fighters may see some recovery in their thinking and memory skills as well as brain structure after they stop fighting, according to a new study published in the September 14, 2022, online ...

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How a patient partnership is propelling cancer research

In the fall of 2018, cancer researcher Corrie Painter began presenting some intriguing early results from a new study on a rare and deadly cancer known as angiosarcoma. She and her fellow scientists hoped that by sharing ...

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Study identifies new prognostic biomarker for heart failure

Bloodstream levels of a protein fragment called endotrophin can be used to predict outcomes in patients with a common form of heart failure, according to a study co-led by researchers at the Perelman School of Medicine at ...

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Nature-inspired peptide shows anti-tumor activity

An Austrian study demonstrates an anti-tumor effect of certain nature-derived cyclic peptides. The study, which has now been published internationally, not only demonstrates the inhibition of cell division by these peptides, ...

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Smaller eggs enhance IVF outcomes for male infertility in mice

A new approach for assisting reproduction in mice when sperm production is faulty has been demonstrated by researchers at RIKEN. It could eventually help human couples who are struggling to conceive by traditional in vitro ...

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A new therapeutic target against the most common lung cancer

TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role has been unknown. Now, a study led by Jordi Alcaraz, lecturer at the Faculty of Medicine ...

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New antiviral therapy may block COVID-19 transmission

By the time you test positive for COVID-19, the SARS-CoV-2 virus has already taken up residence in your respiratory system. With each breath, you expel invisible viral particles into the air—a process known as viral shedding. ...