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Self-amplifying mRNA vaccines appear safe in lab and animal tests

mRNA vaccines contain instruction codes for making parts of pathogenic viruses. Can so-called self-amplifying types of such vaccines form unwanted and dangerous connections with other viruses? Yes, say Wageningen virologists ...

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How a bacterium supports healing of chronic diabetic wounds

There are many important reasons for keeping cuts and sores clean, but new research from the Perelman School of Medicine at the University of Pennsylvania shows that a certain bacterium, Alcaligenes faecalis (A. faecalis), ...

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New protein discovery may influence future cancer treatment

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of ...

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Study debunks link between moderate drinking and longer life

Probably everyone has heard the conventional wisdom that a glass of wine a day is good for you—or you've heard some variation of it. The problem is that it's based on flawed scientific research, according to a new report ...

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Guideline on management of central airway obstruction released

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on central airway obstruction (CAO). Published in the journal CHEST, the guideline contains 12 evidence-based recommendations to ...

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Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

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Understanding the expanded role of clinical ethicists

The COVID-19 pandemic brought many troubling ethical issues to the frontlines of clinical care, creating significant distress for clinicians, patients, and families. Behind the scenes, clinical ethicists managed those issues ...

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Bone transplant could resolve aging jaw defects

Tohoku University scientists in Japan have made a scaffold that supports the growth of new bone in large jaw defects in mice. Their findings, published in the journal PNAS Nexus, bring scientists one step closer to addressing ...

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Researchers developing eyedrops to treat cataracts

Many years ago, I began my Ph.D. with the firm resolve of finding a cure for cataracts—not in several years or decades, but within the duration of my Ph.D. Such was my enthusiasm and naivety. Decades later, though, that ...

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Investigating the role of dopamine circuits in habit formation

Scientists have uncovered how dopamine connects subregions of the striatum essential for habit formation, according to a Northwestern Medicine study published in Cell Reports, findings that may change the overall understanding ...

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Innate immunity: The final touch for antimicrobial defense

If bacteria enter the body, it often takes just a few minutes for the innate immune system to recognize them as foreign and set the immune defense in motion. Receptors of the immune system that recognize bacterial cell wall ...

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The tumor environment can affect breast cancer prognosis

The environment in which breast cancer arises—the interplay between the patient's BMI, tumor size and cancer-specific proteins—is of importance for the prognosis. This is shown in a study from Lund University in Sweden. ...

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Researchers grow 'synthetic' embryo with brain and beating heart

Researchers from the University of Cambridge have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body—a new avenue for recreating the first ...

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New generation of COVID vaccine shows promising results

Researchers at Karolinska Institutet are developing a coronavirus vaccine designed to be less sensitive to mutations and equipped for future strains. The vaccine showed promising results in mice in a newly published study ...

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New role of immune cells in liver regeneration identified

If liver tissue has to be removed due to cancer or another liver disease, the organ usually regenerates quickly, soon becoming fully functional once again. Medical science has not yet completely understood the complex processes ...

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Rehabilitation method to improve taste sensitivity

Many patients suffer from taste disorders due to a variety of causes, and in recent years the number of such patients has skyrocketed even further due to the COVID-19 epidemic. However, treatments to improve taste sensitivity ...

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Discovery suppresses progression of kidney fibrosis

Webster Santos is determined to find a way to halt kidney fibrosis, a condition caused by persistent inflammation and assault to the kidney. The disorder leads to kidney disease, itself a pathway to kidney failure, also known ...