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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

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Study highlights association between urinary and vaginal pathogenic E. coli in recurrent cystitis

The human body hosts a diverse array of microorganisms that maintain a delicate balance crucial for overall health. This microbial harmony can be disrupted by factors such as infections, aging, and hormonal changes, leading ...

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Protein droplets likely don't cause Parkinson's, study suggests

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...

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Promising new options for treating aggressive prostate cancer

Cedars-Sinai Cancer investigators have identified two promising new treatment options for men with recurrent prostate cancer—both of which helped patients live longer without their disease progressing than the current standard ...

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Bat genes found to be key against COVID, cancer

Bats have acquired remarkable traits throughout their evolution. They're the only mammals that can fly, and they live much longer than other animals their size. But perhaps most impressive is their robust immune system. It ...

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New molecule to fight against transthyretin amyloidosis

Researchers from IBB-UAB have developed a second-generation molecule that significantly improves the stabilization and inhibition of the aggregation of proteins involved in Transthyretin Amyloidosis (ATTR), a group of minority ...

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New cancer therapy target stops tumor cells from sharing resources

Researchers at University of California San Diego have discovered a process in which liver cells share molecules via vesicle exchange in order to multiply under conditions that would ordinarily suppress cell proliferation. ...

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Study finds serotonin reduction causes long COVID symptoms

Patients with long COVID—the long-term symptoms like brain fog, fatigue, or memory loss in the months or years following COVID-19—can exhibit a reduction in circulating levels of the neurotransmitter serotonin, according ...

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Tirzepatide weight-loss study shows promising results

After 12 initial weeks of weight loss with intensive lifestyle intervention alone, participants in the SURMOUNT-3 study who were randomly assigned to tirzepatide for 72 weeks achieved a total mean reduction in baseline body ...

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Zooming in on rare bone cells that drive osteoporosis

Mayo Clinic researchers have developed a new high-resolution, analytical technique to identify the rare senescent bone cells that are known to drive osteoporosis. Senescent cells are malfunctioning cells that build up as ...