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Immunology news
Oncology & Cancer
Researchers find difference in pancreatic cancer cells, offering new hope for immunotherapy effectiveness
A new study has found that pancreatic cancer cells are different based on their location in the pancreas, providing new information about tumors that could lead to better targeted treatments.
50 minutes ago
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Arthritis & Rheumatism
Patients with rheumatoid arthritis have unique and complex autoantibody patterns, study reveals
Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease. Researchers at Utrecht University unveiled the complexity of these antibodies using ...
10 hours ago
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Gene expression analyses identify potential drivers of chronic allergic inflammation
Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, ...
19 hours ago
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Study finds some people have a uniquely human gene that enhances immune function
University at Buffalo researchers have found that the active form of a gene promotes a broad range of protective traits. The gene is found in 75% of the population and is known to protect against neurodegeneration. Now, UB ...
23 hours ago
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Study finds Bcl6 protein is an important transcription factor for formation of certain dendritic cells
While previous studies have investigated the function of the protein Bcl6 in dendritic cells—in some cases with varying results—a new study published in Nature Communications has sought to harmonize the sometimes contradictory ...
21 hours ago
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Development in cancer treatment focuses on re-educating cells to combat resistance
In a development in cancer research, scientists are exploring new therapeutic strategies that move beyond traditional cytotoxic treatments, which have historically targeted uncontrolled cell proliferation.
21 hours ago
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Study highlights importance of early interventions to combat HIV
A study has compared the development of HIV reservoirs—locations in the body where the virus persists in a latent state—between patients who receive either early or late medical interventions. The findings highlight the ...
22 hours ago
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Targeting protein interactions may boost antitumor immunity in breast cancer
A multi-institutional team of investigators has discovered that targeting a specific protein interaction within immunosuppressive breast cancer cells may increase antitumor immune responses in otherwise difficult to treat ...
23 hours ago
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New gene signature could transform immunotherapy for gastrointestinal cancers
Despite significant progress in treating gastrointestinal (GI) cancers through surgical resection, chemotherapy, radiotherapy, and targeted therapy, the objective response rate (ORR) for immune checkpoint inhibitor (ICI) ...
17 hours ago
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Unlocking the immune system: cGAS-STING pathway offers new hope for cancer treatment
Cancer immunotherapy, which leverages the body's immune system to target tumors, has emerged as a pivotal strategy in oncology. This paradigm shift from conventional treatments offers a more precise method to neutralize cancer ...
20 hours ago
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New method rapidly reveals how protein modifications power T cells
Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, molecules called phosphate groups are constantly ...
Apr 29, 2024
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Protein responsible for genetic inflammatory disease identified
A team of researchers led by Dr. Hirotsugu Oda at the University of Cologne's CECAD Cluster of Excellence for Aging Research has discovered the role a specific protein complex plays in certain forms of immune dysregulation. ...
Apr 29, 2024
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Cancer cell–immune cell interactions can predict immunotherapy response
By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with ...
Apr 29, 2024
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Researchers discover enzymes that open new path to universal donor blood
The quest to develop universal donor blood has taken a decisive step forward. Researchers at DTU and Lund University have discovered enzymes that, when mixed with red blood cells, are able to remove specific sugars that make ...
Apr 29, 2024
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Scientists develop new organoid model to study thymus function
Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus. The organoids are derived from mouse thymus tissue, specifically model thymic epithelial cells (TECs). These cells ...
Apr 29, 2024
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Immune cell interaction study unlocks novel treatment targets for chikungunya virus
Researchers have long known that the body's immune system plays a critical role in fighting off chikungunya virus (CHIKV), but how exactly immune cells coordinate their response has been a mystery—until now.
Apr 29, 2024
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Researchers uncover molecular mechanism of natural killer cell dysfunction in Hodgkin lymphoma
A multidisciplinary research team comprising the Griffith Institute for Drug Discovery (GRIDD, Griffith University), Mater Research (based at the Translational Research Institute) and The University of Queensland's (UQ) Frazer ...
Apr 29, 2024
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Study reveals interaction mechanism between intestinal microbial environment and tumor immune microenvironment
Colorectal cancer stands as one of the leading malignancies in the digestive system, ranking third and second in terms of new cases among men and women worldwide, respectively. Given the high incidence of this disease and ...
Apr 29, 2024
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Component of keto diet plus immunotherapy may reduce prostate cancer
Adding a pre-ketone supplement—a component of a high-fat, low-carb ketogenic diet—to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University ...
Apr 27, 2024
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Blood test might someday diagnose early MS
An early marker of multiple sclerosis could help doctors figure out who will eventually fall prey to the degenerative nerve disease, a new study says.
Apr 27, 2024
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