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Immunology news

Diseases, Conditions, Syndromes

Viruses found hiding in lungs' immune cells long after initial illness

Doctors have long known that children who become seriously ill with certain respiratory viruses such as respiratory syncytial virus (RSV) are at elevated risk of developing asthma later in life. What they haven't known is ...

Oncology & Cancer

Curbing blood cancers by teaching immune cells to kill mutant stem cells

Blood stem cells, which give rise to all of our blood cell types, undergo a quality assurance process after they're born. As the lab of Leonard Zon, MD, director of the Stem Cell Research program at Boston Children's, has ...

Cardiology

New cardiovascular disease risk marker discovered in older women

Researchers at Karolinska Institutet have identified a new potential risk marker for cardiovascular disease in women. A new study shows an association between low levels of an anti-inflammatory antibody and the risk of heart ...

Oncology & Cancer

Blood cancers: Expert explains what you need to know

Blood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.

Oncology & Cancer

What is CAR-T cell therapy? Oncologist explains

Roughly 635,000 new cases of lymphoma were diagnosed worldwide, according to the World Cancer Research Fund International's most recent report. Survival rates for aggressive lymphomas have improved significantly thanks to ...

Immunology

Circadian rhythm disruption linked to lung inflammation

In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption ...

Genetics

Ancient genomes reveal immunity adaptation in early farmers

Research from the Francis Crick Institute published today in Current Biology has revealed that diversity in genes coding for immunity may have facilitated adaptation to farming lifestyles in prehistoric periods.

Arthritis & Rheumatism

Points to consider when using interferon assays

Interferons are type of protein called a cytokine. They have important roles in the immune system. Interferons are split into three distinct families—Type I, Type II, and Type III. Due to their role in autoimmunity, Type ...

HIV & AIDS

New directions for HIV treatment

Northwestern Medicine scientists have identified a new compound which could inform future HIV cure strategies, according to research published in Science Advances.

Immunology

New intracellular 'smoke detector' discovered

Researchers at the Universities of Bonn and Singapore have discovered a new intracellular "smoke detector." The sensor warns of damage to the mitochondria—the microscopic power plants that supply the cell with energy. If ...

Genetics

Insights into causes of rare genetic immune disorders

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations ...

Medical research

Restoration of immune defense in liver disease

Patients suffering from chronic liver disease don't respond to vaccination and are at high risk of viral infections. In these patients, virus-specific T-cells are defect and unable to eliminate viral pathogens. A research ...

Psychology & Psychiatry

Immune system cells in the gut linked to stress-induced depression

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked ...

Oncology & Cancer

Researchers identify key source of T cell 'exhaustion'

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...

Diseases, Conditions, Syndromes

Runaway immune reactions can cause long COVID breathing problems

Stanford Medicine researchers have found a mechanism behind one of the most common symptoms of long COVID—shortness of breath. Post COVID-19 breathing problems are caused by a condition known as lung fibrosis, when damaged ...

Oncology & Cancer

Can lymph nodes boost the success of cancer immunotherapy?

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells. But new findings from a clinical trial by researchers at UC San Francisco and Gladstone Institutes shows ...