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Running the numbers shows ivermectin could help beat malaria
When a stranger from Spain called Cassidy Rist in her first months at Virginia Tech, she almost didn't take the meeting. The caller was Carlos Chaccour, a physician at the University of Navarra who worked on global health ...
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Nitric oxide rewires gene expression in the brain, offering new insight into Alzheimer's disease
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome—the working portion of our DNA that helps make each person unique. Put simply, a single ...
1 hour ago
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Medical research news
Common epilepsy drug disrupts early brain growth in human organoids after 30-day exposure
It is known that the antiepileptic drug valproate increases the risk of developmental disorders in unborn children. A study conducted by the Karlsruhe Institute of Technology (KIT), the Heidelberg Academy of Sciences and ...
4 minutes ago
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Weight loss drug semaglutide helps patients who do not respond to bariatric surgery, research finds
Metabolic/bariatric surgery is a highly effective treatment for people living with severe obesity and/or metabolic health conditions, which works through changing the anatomy of the digestive system and thereby changing the ...
44 minutes ago
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Ovarian cancer cells use stress hormone signaling to shut down immune system, research reveals
When activated in ovarian cancer cells, the receptor for the body's primary stress hormone alters the tumor environment in ways that blunt immune response, according to new research led by UT Southwestern Medical Center. ...
1 hour ago
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Gut-lung microbe shifts may explain clozapine's severe bowel and lung side effects
Schizophrenia is a severe mental health disorder characterized by hallucinations, false and rigid beliefs (i.e., delusions), impaired mental functions, disorganized speech and, in some cases, repetitive body movements. This ...
Study reveals brain changes linked to alcohol addiction recovery
Scientists say they've uncovered striking new evidence of how alcohol addiction impacts the brain's learning systems—and how those systems may slowly adapt during recovery—in a new study published in Clinical Neurophysiology ...
1 hour ago
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A single dose of psilocybin eased depression symptoms for months, our study found
A single dose of psilocybin eased symptoms of depression within days, with benefits lasting for more than three months compared to placebo, our new study has found.
2 hours ago
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COVID-19 mRNA vaccine plus immune system enhancer may reduce need for repeated boosters, say researchers
In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, improved the duration ...
7 hours ago
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Researchers identify avenue for enhanced GLP-1-induced weight loss
A team of researchers at the National Institutes of Health (NIH) have unveiled new details about the events GLP-1 receptor agonists trigger within neurons, which have been largely unexplored until now. A study in mice identified ...
7 hours ago
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Why energy fades with age: Missing membrane lipid may destabilize mitochondria
Why do cells age—and why do we lose our energy and vitality as we get older? This question is one of the central challenges of modern biomedicine. The focus is particularly on mitochondria—tiny cellular organelles long known ...
20 hours ago
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Mental disorders have nearly doubled since 1990, now affecting 1.2 billion people worldwide
Nearly 1.2 billion people worldwide are living with a mental disorder, nearly double the number recorded in 1990. According to a new study, this stark rise has placed mental disorders as the leading cause of disability globally, ...
18 hours ago
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Child death rates in the United States have increased, study finds
The overall death rate of children and adolescents in the United States increased 6.6% between 2020 and 2023, researchers reported on May 13 in the New England Journal of Medicine. Many of the top causes of death in young ...
19 hours ago
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'Pink noise' can help make anesthesia work better during surgery
In the brain, specific electrical waves are associated with different states of consciousness. For instance, delta waves—also known as slow waves—are especially prevalent during deep sleep, as well as during states of unconsciousness ...
20 hours ago
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The brain's night shift: How sleep, waste clearance and dementia may be linked
Why are conditions such as chronic stress, depression, cardiovascular disease, fragmented sleep, and aging all associated with a higher risk of dementia? In a new review piece in Science, University of Rochester Medicine ...
22 hours ago
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Scientists capture 'housekeeping' immune cells attacking live melanoma
Scientists at the Garvan Institute of Medical Research have captured, for the first time, "housekeeping" immune cells actively attacking and engulfing live melanoma cells—a discovery that could change the way we approach ...
20 hours ago
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Duration of depression may influence how severely the disease alters the brain
Depression affects about 5.8% of the Brazilian population and presents a wide range of symptoms, intensities, and durations. A study published in Scientific Reports involving patients with major depressive disorder demonstrated ...
21 hours ago
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'Origami' method could speed up diagnosis of neurodegenerative disease
Researchers have developed a technique that can identify errors caused by mutations linked to a range of genetic disorders, including forms of muscular dystrophy, Huntington's disease and amyotrophic lateral sclerosis (ALS), ...
21 hours ago
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The bigger the reward, the faster we learn, researchers find
Scientists long assumed that learning speed depends primarily on our experience—how many times we try and succeed—not the size of the reward. We become better at poker because we keep playing and winning, regardless of the ...
22 hours ago
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Smartphone data predict smoking cravings and lapses, with potential to treat addiction and other conditions
Minuscule movement patterns collected from smartphones and often undetectable to humans have been used to predict cravings and compulsive behaviors with groundbreaking accuracy—potentially offering timely and bespoke treatment ...
21 hours ago
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