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Pig transplant research yields a surprise: Bacon safe for some people allergic to red meat

Some people who develop a weird and terrifying allergy to red meat after a bite from a lone star tick can still eat pork from a surprising source: Genetically modified pigs created for organ transplant research.

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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

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Protein droplets likely don't cause Parkinson's, study suggests

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...

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Tracking early signs of Alzheimer's pathology in a mouse model

About two-thirds of the risk for Alzheimer's disease (AD) is thought to arise from genetic influences, but about a third could be influenced by environment and lifestyle, opening the door for behavioral interventions that ...

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Beating seizures by jamming the cellular circuitry

Research at UC San Francisco has shown for the first time how the commonly prescribed seizure and pain medication, gabapentin, acts inside of cells, opening the door to new, more effective treatments for diseases like epilepsy ...

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Tunable bonds: A step towards targeted At-211 cancer therapy

Astatine is the least abundant element on Earth, and all of its known isotopes have a half-life of less than 8 hours. One astatine isotope, astatine-211 (At-211), emits alpha particles and shows promise as a cancer therapy. ...

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Why new cancer treatment discoveries are proliferating

In the five years since the FDA's initial approval of chimeric antigen receptor (CAR) T cell therapy, Penn Medicine has gleaned 20 additional approvals related to drugs and techniques to treat or detect cancer.

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Examining the secrets of the microbiome

You're more microbe than human, at least by the numbers. The human body has about 37 trillion cells, but it's home to many more microbes—the gut alone has 100 trillion of them. Swimming and squirming inside your tummy are ...

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Paralysed man walks again via thought-controlled implants

A paralyzed man has regained the ability to walk smoothly using only his thoughts for the first time, researchers said on Wednesday, thanks to two implants that restored communication between brain and spinal cord.

Medical research

Oxygen restriction helps fast-aging lab mice live longer

For the first time, researchers have shown that reduced oxygen intake, or "oxygen restriction," is associated with longer lifespan in lab mice, highlighting its anti-aging potential. Robert Rogers of Massachusetts General ...

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New vaccine concept against SARS-CoV-2 successfully tested

Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19. This vaccine is based on a modified coronavirus that can enter body cells and trigger an effective immune response but cannot ...