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Policy paper calls for evidence-based public health approach to cannabis regulation

A public health approach is necessary to address the legal, medical, and social complexities of cannabis use, says the American College of Physicians (ACP) in a new policy paper released today.

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Data from largest Phase III trial of pre-symptomatic Alzheimer's disease now shared with scientists around the world

Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition. The ...

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

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Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

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New method predicts the right treatment for breast cancer patients

Researchers at Karolinska Institutet have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not. The cell-based method has been tested on patients ...

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Investigating the neural mechanisms behind itchy eyes in rodents

Anyone suffering dry skin, eczema, or insect bites will know the unpleasant effects of itchy skin. While the physiological mechanisms behind itching sensations on the skin are well understood, corresponding signals for the ...

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Identifying pathways to slow cardiac aging

Cardiovascular disease is the leading cause of death worldwide, and is caused in part by age-related cardiac structural dysfunction. A team of bioengineers in Professor Adam Engler's lab at the University of California San ...

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When the body's B cell training grounds stay open after hours

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities. ...

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Researchers reveal lipidome atlas of developing heart

The heart, an indispensable organ with fascinating development biology, is the first organ to become functional in the developing mammalian embryo. Cardiac lipid metabolism is intricately connected with heart physiology. ...

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High-energy X-rays leave a trace of destruction in bone collagen

A team of medical researchers at Charité-Universitätsmedizin has analyzed damage by focused high energetic X-rays in bone samples from fish and mammals at BESSY II. With a combination of microscopy techniques, the scientists ...

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Acids help against airborne viruses, finds interdisciplinary study

A new study by various Swiss universities, including EPFL, shows that aerosols in indoor air can vary in acidity. This acidity determines how long viruses such as influenza and SARS-CoV-2 remain infectious in the air—with ...

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A protective probiotic for ALS found

A probiotic bacterium called Lacticaseibacillus rhamnosus HA-114 prevents neurodegeneration in the C. elegans worm, an animal model used to study amyotrophic lateral sclerosis (ALS).

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Investigators discover new mechanism to boost RNA therapies

Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells—cells that control your heartbeat—can "fight back" against therapies to biologically correct abnormal heartbeat ...

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Study on the origins of Omicron retracted

Universitätsmedizin Berlin reported new findings on the origins of the SARS-CoV-2 variant Omicron. The team led by Prof. Jan Felix Drexler has now retracted the article, which was published in the journal Science.