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Data from largest Phase III trial of pre-symptomatic Alzheimer's disease now shared with scientists around the world

Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition. The ...

Medical research

Policy paper calls for evidence-based public health approach to cannabis regulation

A public health approach is necessary to address the legal, medical, and social complexities of cannabis use, says the American College of Physicians (ACP) in a new policy paper released today.

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

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Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

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During sleep, brain regions synchronize to create motor memory

When the Golden State Warriors' Steph Curry makes a free throw, his brain draws on motor memory. Now researchers at UC San Francisco (UCSF) have shown how this type of memory is consolidated during sleep, when the brain processes ...

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A way to make asthma drugs last longer

For many, inhalers are a sort of miracle drug. From gasping for air one minute, to breathing normally the next, patients can experience significant relief after one or two puffs. What few people realize is that these life-saving ...

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New aptamer drug for bone anabolic therapies

A research team led by Hong Kong Baptist University (HKBU) has identified a molecular target for bone anabolic therapies using a selected aptamer that serves as an inhibitor of sclerostin, a protein that prevents bone growth. ...

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Cholesterol-lowering statins found to impair bone quality in mice

Researchers from the Complexity Science Hub (CSH) and the Medical University of Vienna (MedUni) have demonstrated for the first time that high doses of cholesterol-lowering statins impair bone quality in mice. The finding ...

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Long COVID: New evidence for cause of fatigue syndrome

The diagnosis and treatment of long COVID syndrome (LCS) is still very difficult, and there is only little knowledge about the factors causing accompanying symptoms. Researchers at the Joint Metabolome Facility of the University ...

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COVID-19: A respiratory mucosal vaccine effective in mice

Less known to the general public, mucosal vaccination via the mucus membranes could provide robust protection against SARS-CoV-2 infections. Immune cells in the nose and lungs are considered better prepared to encounter and ...

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Looking for an early sign of LATE: New insights into the pathology

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), ...

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RXR, the cell protein that keeps blood stem cells young and fit

The cell protein retinoid X receptor (RXR) is a key factor in the maintenance of hematopoietic stem cells, the immature stem cells that give rise to all the blood cell lineages. RXR ensures that these cells remain youthful ...

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Does what you drink affect your risk of urinary incontinence?

Urinary incontinence affects nearly 20% of women aged older than 50 years. Many factors can influence a woman's risk of urinary incontinence. A new study suggests that despite some commonly held misconceptions, the consumption ...

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Study shows limited diversity in psychophysiology trials

A new study from Oregon State University has found that psychophysiology studies show a significant lack of diversity among their participants, making their results less applicable across different communities and cultures.