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Self-amplifying mRNA vaccines appear safe in lab and animal tests

mRNA vaccines contain instruction codes for making parts of pathogenic viruses. Can so-called self-amplifying types of such vaccines form unwanted and dangerous connections with other viruses? Yes, say Wageningen virologists ...

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How a bacterium supports healing of chronic diabetic wounds

There are many important reasons for keeping cuts and sores clean, but new research from the Perelman School of Medicine at the University of Pennsylvania shows that a certain bacterium, Alcaligenes faecalis (A. faecalis), ...

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New protein discovery may influence future cancer treatment

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of ...

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Study debunks link between moderate drinking and longer life

Probably everyone has heard the conventional wisdom that a glass of wine a day is good for you—or you've heard some variation of it. The problem is that it's based on flawed scientific research, according to a new report ...

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Guideline on management of central airway obstruction released

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on central airway obstruction (CAO). Published in the journal CHEST, the guideline contains 12 evidence-based recommendations to ...

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Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

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Investigating the role of fatty acids in cancer cell survival

Northwestern Medicine investigators have discovered that a particular enzyme is essential for regulating cancer cell survival and metastasis under cellular stress, findings that were published in the Proceedings of the National ...

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New insights on the genetic underpinnings of the vocal tract

Despite its importance for speaking, breathing, and eating, we know relatively little about the genetic underpinnings of the human vocal tract, a system made up of cavities and organs such as the tongue, the larynx, and the ...

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Mapping human brain development

The human brain is probably the most complex organ in the entire living world and has long been an object of fascination for researchers. However, studying the brain, and especially the genes and molecular switches that regulate ...

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Scientists discover protein partners that could heal heart muscle

Scientists at the UNC School of Medicine have made a significant advance in the promising field of cellular reprogramming and organ regeneration, and the discovery could play a major role in future medicines to heal damaged ...

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Brain-like organoids grown in a dish provide window into autism

Whatever you do, don't call them "mini-brains," say University of Utah Health scientists. Regardless, the seed-sized organoids—which are grown in the lab from human cells—provide insights into the brain and uncover differences ...

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Novel technique reveals surprising way to suppress tumor cells

By analyzing key enzymes in a new way, an international team led by researchers at Weill Cornell Medicine has discovered how a well-known signaling molecule can either stimulate or suppress tumor growth depending on where ...