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Self-amplifying mRNA vaccines appear safe in lab and animal tests

mRNA vaccines contain instruction codes for making parts of pathogenic viruses. Can so-called self-amplifying types of such vaccines form unwanted and dangerous connections with other viruses? Yes, say Wageningen virologists ...

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How a bacterium supports healing of chronic diabetic wounds

There are many important reasons for keeping cuts and sores clean, but new research from the Perelman School of Medicine at the University of Pennsylvania shows that a certain bacterium, Alcaligenes faecalis (A. faecalis), ...

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Study debunks link between moderate drinking and longer life

Probably everyone has heard the conventional wisdom that a glass of wine a day is good for you—or you've heard some variation of it. The problem is that it's based on flawed scientific research, according to a new report ...

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New protein discovery may influence future cancer treatment

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of ...

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Guideline on management of central airway obstruction released

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on central airway obstruction (CAO). Published in the journal CHEST, the guideline contains 12 evidence-based recommendations to ...

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Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

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Targeting ion channels to manage osteoarthritis pain

Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy to manage osteoarthritis pain, according to a Northwestern Medicine study published in Cell Reports.

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Time-restricted eating improves health of firefighters

Firefighters are the heroes of our society, protecting us around the clock. But those 24-hour shifts are hard on the body and increase the risk of cardiometabolic diseases, such as heart disease and diabetes, as well as cancer. ...

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Finding an RNA target and tool to fight premature aging

Progeroid syndromes are a group of rare genetic disorders that cause signs of premature aging in children and young adults, such as Werner Syndrome and Hutchinson Gilford Progeria Syndrome. Patients affected by progeroid ...

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Weighted blankets found to increase melatonin

A new study from Uppsala University shows that using a weighted blanket at bedtime increases melatonin in young adults. This hormone increases in response to darkness, and some evidence suggests that it promotes sleep. The ...

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Non-opioid compounds squelch pain without sedation

A newly identified set of molecules alleviated pain in mice while avoiding the sedating affect that limits the use of opiates, according to a new study led by researchers at UC San Francisco. The molecules act on the same ...

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Another monkey virus could be poised for spillover to humans

An obscure family of viruses, already endemic in wild African primates and known to cause fatal Ebola-like symptoms in some monkeys, is "poised for spillover" to humans, according to new University of Colorado Boulder research ...