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Immunology news
Oncology & Cancer
Engineered dendritic cells boost cancer immunotherapy
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.
5 hours ago
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Genetics
Individual genetic differences can render some antibody-based therapies ineffective
Antibody-based therapies are used to treat numerous diseases, from cancer to rheumatic disorders and multiple sclerosis. Antibodies recognize and bind to very specific structures. This allows them to direct active substances ...
5 hours ago
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Microbiome may aid in healthy pregnancies by training maternal immune system
Gut microbes may play a key role in training a mother's immune system to adapt to the developing fetus during pregnancy, according to a preclinical study by Weill Cornell Medicine investigators.
2 hours ago
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Astrocytes found to aid spinal cord repair by signaling immune response
Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple sclerosis. Their study, ...
9 hours ago
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Liver cell reprogramming boosts T cell function in aging immune systems
As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, making people more susceptible to a variety of infections.
9 hours ago
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COVID-19 virus manipulates host cell RNA to shut down the immune system, study reveals
Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered that SARS-CoV-2, the virus that causes COVID-19, uses a sophisticated tactic to evade the human body's defense system. In addition to ...
9 hours ago
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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses
mRNA vaccines, such as those used against COVID-19, are effective at generating antibody responses. These antibodies are produced through specialized immune structures called germinal centers, but until now it was not fully ...
10 hours ago
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Chronic fatigue syndrome linked to widespread energy, immune and vascular changes
New Australian research has identified simultaneous abnormalities across multiple biological systems in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
12 hours ago
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Black patients diagnosed with aggressive leukemia experience worse outcomes
Compared with white patients, Black patients with an aggressive form of leukemia—called acute myeloid leukemia (AML)—were on average more than five years younger at diagnosis and more than 30% more likely to die of their ...
8 hours ago
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New antibody design blocks cytomegalovirus from hiding from the immune system
Researchers at Texas Biologics at The University of Texas at Austin, working with scientists internationally, have made an important discovery that could improve treatment of human cytomegalovirus (HCMV), a common but overlooked ...
Dec 16, 2025
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AI that predicts sequences within antibodies could lead to new therapeutic treatments
A new artificial intelligence model could help design antibodies that better protect the body against viruses and disease. The AI model, known as ImmunoMatch, can predict and identify correct protein pairings within antibodies, ...
Dec 16, 2025
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Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.
Dec 16, 2025
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New understanding of T cell receptors may improve cancer immunotherapies
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full ...
Dec 16, 2025
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Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'
Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.
Dec 16, 2025
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Evaluating the impact of heat-inactivated bacteria on age-related inflammation
The process of aging is associated with a decline in immune functions and persistent low-level inflammation. Now, researchers from Japan have discovered a strain of Lentilactobacillus capable of preventing and even reversing ...
Dec 16, 2025
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Changing the paradigm on hypermobile Ehlers-Danlos Syndrome: Connective tissues don't tell the whole story
Recent research from the Medical University of South Carolina laboratory of Russell Norris, Ph.D., challenges the notion that hypermobile Ehlers-Danlos Syndrome (hEDS) is an isolated connective tissue disorder, revealing ...
Dec 16, 2025
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High stakes of early immune development revealed—and a potential probiotic fix
Antibiotics are powerful treatments that have saved countless lives over the course of decades. New findings from Scripps Research have identified a way to preserve healthy immune development even when infants need antibiotic ...
Dec 16, 2025
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Doctors provide new hope for pancreatic cancer patients with less invasive radiofrequency ablation
UT Health San Antonio Multispecialty and Research Hospital became the first in South Texas to use an emerging and less-invasive treatment called radiofrequency ablation on a comorbid patient with a pancreatic cancer tumor ...
Dec 16, 2025
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Soil bacteria and fungi emerge as top predictors of childhood allergic disease
The unique blend of fungi and bacteria in a region's soil may be the strongest factor explaining its rates of childhood allergic disease, with certain assemblages of soil critters appearing linked with better health outcomes, ...
Dec 16, 2025
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Decoding long COVID: Investigators reveal why the body keeps fighting the war
A new study from investigators at Beth Israel Deaconess Medical Center (BIDMC) sheds light on why some people never fully recover from COVID-19.
Dec 15, 2025
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How the immune system keeps mucosal fungi in check
The microbiome not only consists of bacteria, but also of fungi. Most of them support human and animal health. However, some fungi also have pathogenic potential. For instance, the yeast Candida albicans can grow in an uncontrolled ...
Dec 15, 2025
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Building a better vaccine: Flu antibodies show expanded role in preventing transmission
Today's influenza vaccines primarily prevent infection in individuals, but new research led by the University of Michigan and the Institut Pasteur suggests that incorporating antibodies generated after infection could lead ...
Dec 15, 2025
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Dramatic drop in HIV-infected immune cells occurs in patient who received cancer treatment
Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at undetectable levels ...
Dec 15, 2025
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Targeting B-cells may boost immunotherapy in liver cancer treatment
Scientists have identified a promising strategy to improve liver cancer immunotherapy: targeting B-cells. While immunotherapy has transformed cancer treatment by activating T-cells—a type of immune cell that fights cancerous ...
Dec 15, 2025
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FDA approves Breyanzi for relapsed, refractory marginal zone lymphoma
The U.S. Food and Drug Administration has approved a new indication for Breyanzi (lisocabtagene maraleucel) for treating adults with marginal zone lymphoma (MZL) who have failed treatment or relapsed after two or more prior ...
Dec 15, 2025
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