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Immunology news

Oncology & Cancer

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

A Cleveland Clinic-led research collaboration between Timothy Chan, MD, Ph.D., Chair of Cleveland Clinic's Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of ...

Diseases, Conditions, Syndromes

New mouse models offer valuable window into COVID-19 infection

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.

Oncology & Cancer

Blood cancers: Expert explains what you need to know

Blood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.

Oncology & Cancer

What is CAR-T cell therapy? Oncologist explains

Roughly 635,000 new cases of lymphoma were diagnosed worldwide, according to the World Cancer Research Fund International's most recent report. Survival rates for aggressive lymphomas have improved significantly thanks to ...

Immunology

Circadian rhythm disruption linked to lung inflammation

In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption ...

HIV & AIDS

'Undetectable' HIV patients could hold key to treatments

A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert.

Immunology

Novel antibodies against Klebsiella pneumoniae identified

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections. Using genetic and functional approaches, the researchers also managed ...

Immunology

Study shows breast milk contains unique set of antibodies

Breast milk from each individual contains a unique assemblage of antibodies that are surprisingly stable throughout lactation and across pregnancies, according to a new Journal of Experimental Medicine study from the University ...

Diseases, Conditions, Syndromes

An immune flaw may cause West Nile virus's deadliest symptoms

Four out of five of people infected with the mosquito-borne West Nile virus (WNV) won't even know it—heartening news when you consider there's no vaccine to prevent the disease nor targeted medications to treat it. However, ...

Medical research

PFAS shown to reduce the activity of immune cells

PFAS are used in many everyday products. This is because PFAS are water- and fat-repellent, heat resistant, and extremely durable. PFAS have been produced since the 1950s and there are now around 10,000 different compounds.

Diseases, Conditions, Syndromes

Researchers discover novel biomarker for sepsis severity

MUSC researchers have identified a novel biomarker that could change the way sepsis is approached and treated. Sepsis, the leading cause of death in intensive care units, is the body's extreme response to an infection and ...

Immunology

New research shows babies' immunological weak spot and strength

A pair of new studies led by researchers at Columbia University explains why babies get so many common respiratory infections and identifies a specialized cluster of immune cells found only in babies that help them better ...

Neuroscience

How the immune system can alter our behavior

Simply the smell of seafood can make those with an allergy to it violently ill—and therefore more likely to avoid it. The same avoidance behavior is exhibited by people who develop food poisoning after eating a certain ...

Immunology

How dendritic cells activate the immune system

The specific or acquired immune system of vertebrates is a powerful weapon against pathogens and pathologically altered body cells. Here, T cells play a special role. After activation, they can systematically kill off target ...

Oncology & Cancer

Biomaterial-delivered one-two punch boosts cancer immunotherapy

Cancer immunotherapy has brought major improvement in patient survival and quality of life, especially with the success of adoptive T cell and immune checkpoint inhibitor therapies. Unfortunately, in contrast to different ...