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Immunology news

Oncology & Cancer

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

A Cleveland Clinic-led research collaboration between Timothy Chan, MD, Ph.D., Chair of Cleveland Clinic's Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of ...

Diseases, Conditions, Syndromes

New mouse models offer valuable window into COVID-19 infection

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.

Oncology & Cancer

Blood cancers: Expert explains what you need to know

Blood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.

Oncology & Cancer

What is CAR-T cell therapy? Oncologist explains

Roughly 635,000 new cases of lymphoma were diagnosed worldwide, according to the World Cancer Research Fund International's most recent report. Survival rates for aggressive lymphomas have improved significantly thanks to ...

Immunology

Circadian rhythm disruption linked to lung inflammation

In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption ...

HIV & AIDS

'Undetectable' HIV patients could hold key to treatments

A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert.

Immunology

Novel antibodies against Klebsiella pneumoniae identified

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections. Using genetic and functional approaches, the researchers also managed ...

Diseases, Conditions, Syndromes

Discovery may lead to personalized medicine for infectious diseases

An infectious disease is a condition in which a microorganism (virus, bacterium, or parasite) manages to penetrate and multiply in the human body, causing direct damage to the body's cells. The damage to the body may also ...

Diseases, Conditions, Syndromes

New research may lead to new types of treatments for leprosy

Leprosy has existed since at least Biblical times, yet scientists still don't know exactly how Mycobacterium leprae causes the disease's symptoms. Though antibiotics can treat the illness, researchers are concerned about ...

Arthritis & Rheumatism

JAK signaling may be behind polymyalgia rheumatica

Janus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study published online June 29 in PLOS Medicine.

Oncology & Cancer

Fecal transplants show promise in improving melanoma treatment

In a world-first clinical trial published in the journal Nature Medicine, a multi-center study from Lawson Health Research Institute, the Centre hospitalier de l'Université de Montréal (CHUM) and the Jewish General Hospital ...

Diseases, Conditions, Syndromes

Fine-tuning antibodies for treating tumors and infections

Antibodies are crucial, not only for treating tumors and infections. Sometimes, however, the immune reaction they trigger can be too strong and end up causing more damage, for example in the case of people infected with COVID-19. ...

Obstetrics & gynaecology

Researchers examine role of B cells in polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a common hormone disorder in women. Studies have shown that the change in hormones is accompanied by variations in immunological B cells. Researchers at Karolinska Institutet have now established ...

Oncology & Cancer

A two-for-one approach to boost melanoma immunotherapy

New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune ...