Alzheimer's disease & dementia

Immune cell defect stimulates Alzheimer's

Defects in the gene TREM2 are linked to increased risk of Alzheimer's disease. The gene is required to activate immune cells called microglia in the brain, which help to eliminate the neurotoxic deposits that are typical ...

Immunology

Scientists develop new mouse model of Hirschsprung's disease

About one in every 5,000 babies is born without enteric neurons in the distal colon resulting in Hirschsprung's disease. Because of the missing neurons, contents of the gut cannot pass normally, resulting in constipation ...

Immunology

Gut immune cells cut inflammation in multiple sclerosis

Researchers at the University of Toronto and UC San Francisco have discovered that the intestine is the source of immune cells that reduce brain inflammation in people with multiple sclerosis (MS), and that increasing the ...

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