Some people living with HIV develop antibodies capable of neutralizing many different strains of the virus. New research links this to immune responses that occur early in infection. The findings, published in PLOS Pathogens, ...
Apr 21, 2026
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While modern life includes many conveniences, humans are still incessantly exposed to a variety of metabolic stresses we have never experienced before. Our immune systems are constantly trying to protect us, and CD8⁺ T cells ...
Apr 20, 2026
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The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body. Yet, even after decades of research on how the ...
Apr 20, 2026
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The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel Prize–winning technology is being adapted to fight cancer, with mRNA vaccines in clinical trials for melanoma, ...
Apr 18, 2026
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Restricting calorie intake in species such as mice, rhesus monkeys, and fruit flies has been shown to extend their lifespans. In some cases, these animals not only live longer, but are also free of disease. But when pushed ...
Apr 17, 2026
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UPMC and University of Pittsburgh clinician-scientists have weaned and kept multiple liver transplantation patients off of all immunosuppressant drugs for more than three years through a first-in-human clinical trial of a ...
Apr 17, 2026
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The immune system acts as a critical sentinel of organismal aging, integrating the sensing of physiological states with the execution of defense and clearance functions. Immunosenescence not only reflects systemic functional ...
Apr 16, 2026
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An innovative gene-editing strategy could establish a new way for the body to manufacture therapeutic proteins—including certain kinds of highly potent antibodies that are naturally difficult to produce—by reprogramming the ...
Apr 16, 2026
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UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation ...
Apr 16, 2026
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Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular ...
Apr 15, 2026
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