In autoimmune diseases, the immune system turns against the body through pathogenic high-affinity B cells or T cells, leading to severe organ damage. Multiple sclerosis (nervous system paralysis), type 1 diabetes (a strong ...
Sep 7, 2026
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Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease of the central nervous system in which the immune system attacks structures in the brain, spinal cord and optic nerve. It mostly affects astrocytes, ...
Sep 7, 2026
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Researchers at Johns Hopkins Medicine have uncovered a critical biological mechanism that helps explain how inflammation is triggered and sustained in a wide range of diseases—highlighting a promising avenue for future therapeutic ...
Sep 5, 2026
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Past studies suggest that a mother-to-be's heightened immune responses during pregnancy are linked to a higher risk of conditions affecting their offspring's brain development. While this association is well documented, the ...
Pancreatic cancer remains one of the most aggressive malignancies, with a particularly poor prognosis even when diagnosed at a localized stage. In a paper published in Nature Reviews Gastroenterology & Hepatology, researchers ...
Sep 4, 2026
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Why do genetic variants that increase the risk of autoimmune disease remain so common in the population?
Sep 11, 2026
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Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine. It is usually treated with steroids, but in some cases, steroids alone are insufficient, ...
Sep 10, 2026
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Seven years ago, Johns Hopkins researchers and their collaborators announced they had found the X cell, a novel immune cell that plays a key role in the development of type 1 diabetes.
Sep 9, 2026
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Autoimmune diseases arise when the immune system mistakenly attacks the body's own tissues. Researchers have long known that these diseases tend to run in families, but the genetic relationships between different autoimmune ...
Sep 4, 2026
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A new study published in The American Journal of Pathology provides new evidence that immune cells enter the retina via the body's standard pathway, identifying PECAM as the gatekeeper and neutrophils as proresolving mediators. ...
7 hours ago
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