Intestinal epithelial cells line the inner wall of the gut, creating a barrier against dangerous bacteria like enteropathogenic E. coli that seek to attach to and destroy this barrier. Such pathogens pose significant risks ...
21 hours ago
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B-cells infiltrating the lungs may be responsible for one of the most common complications in lung transplantation, which can lead to rejection, according to a study published in the Journal of Clinical Investigation.
22 hours ago
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Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have revealed a powerful new bone marrow atlas that will offer the public a first-of-its-kind ...
May 6, 2024
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T cells—the body's foot soldiers against invaders, ranging from everyday infections to cancers—are integral to many successful immunotherapies. However, a frustrating factor is that immunotherapies do not always work.
May 6, 2024
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One of the main roles of the spleen is to help the body's immune system fight infections. The spleen does this through producing and regulating antibodies—antibody production is negatively affected in various conditions, ...
May 6, 2024
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In a study published in Science on May 3, researchers unveiled two responding patterns of tumor-infiltrating B cells with therapeutic implications.
May 6, 2024
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B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), disproving the previous consensus that T cells ...
May 6, 2024
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Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs destructive immune reactions.
May 3, 2024
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The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow ...
May 3, 2024
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Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T–cell immunotherapy, where a patient's own immune cells are re-engineered to attack cancer ...
May 3, 2024
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