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Genetics news
Oncology & Cancer
Gene variants foretell the biology of future breast cancers, study finds
A Stanford Medicine study of thousands of breast cancers has found that the gene sequences we inherit at conception are powerful predictors of the breast cancer type we might develop decades later and how deadly it might ...
5 hours ago
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Oncology & Cancer
Cancer can be caused by reversible molecular changes, study shows
Though 1 in 2 people will develop some form of cancer in their lifetime, there's still much we don't know about this disease. But thanks to continued research efforts, we keep learning more about the biology of cancer. One ...
6 hours ago
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Too much or too little: The impact of protein dosage on fetal development
New research from the University of Lausanne reveals that both the excess and the deficiency of a single protein can lead to severe intellectual deficiencies. The discovery offers critical insights for early diagnosis of ...
8 hours ago
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Ongoing clinical trials offer hope for people born with genetic mutation behind fibrodysplasia ossificans
Several teams of medical researchers are currently testing new therapies for slowing or stopping the excess or runaway bone growth associated with fibrodysplasia ossificans progressive (FOP)—a rare bone disease.
Systematic survey reveals unannotated human gene that's overexpressed in pituitary tumors
A recent study focuses on the Ly-6 antigens, a family of proteins that contain a conserved LU domain. These antigens have been associated with stem cells and cancer stem cells. The mouse Ly-6A (also known as Sca-1) is a well-known ...
3 hours ago
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Q&A: Understanding protein mutations that affect gene expression to promote cancer progression
Graduate student Hillary Layden studies transcriptional control of cancer in the lab of Scott Hiebert, Hortense B. Ingram Chair in Cancer Research and professor of biochemistry.
6 hours ago
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Engineered DNA 'warhead' targets a common cancer mutation
Tumor protein P53 (TP53) plays an important role in suppressing the growth of tumors. Mutations in the gene for TP53 can have a disastrous effect, hampering the body's ability to fight tumors and even encouraging their growth. ...
7 hours ago
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Researchers create comprehensive transcriptional atlas of human adenomyosis
Adenomyosis is a poorly understood gynecological disorder with limited treatment options. A new study employed single-cell RNA sequencing and spatial transcriptomics to map transcriptional alterations across different regions ...
2 hours ago
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Researchers discover that a type of childhood leukemia originates during fetal development
A team of researchers has demonstrated that some childhood leukemias originate during embryonic development, although they do not manifest after a few months after birth.
6 hours ago
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Research team creates mice that better reflect human genetic variation
The great majority of how we understand human disease, and attempt to cure it, derives from mice genetically fashioned to be prolific breeders, docile and easy to handle—all qualities that have made it the favorite tool ...
May 29, 2024
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Researchers uncover surprising role of opioid receptors in gut development
Researchers at Rice University have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the "brain in the gut." This discovery challenges ...
May 29, 2024
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CRISPR-based mapping uncovers 'switches' for immune genes central to health
Healthy T cells are the foundation of a balanced immune system. They can spring into action to fight off infections or cancer, but keep from becoming so activated that they hurt the very cells they're meant to protect, as ...
May 29, 2024
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The use of new technologies expands understanding of brain tumors in children
A study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification. The research results were published in the journal Acta Neuropathologica Communications. ...
May 29, 2024
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Scientists generate the first complete chromosome sequences from non-human primates
A team of researchers have generated the first complete chromosome sequences from non-human primates. Published in Nature, these sequences uncover remarkable variation between the Y chromosomes of different species, showing ...
May 29, 2024
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Genetic mosaicism more common than thought, study shows
Blood stem cells from healthy people carry major chromosomal alterations, suggesting we are all genetic mosaics, according to a new study from EMBL and the Max Delbrück Center.
May 28, 2024
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Targeting 'monster cancer cells' could reduce recurrence rates after cancer therapy
MUSC Hollings Cancer Center researchers have unlocked a discovery that could help to explain why cancer can recur in patients who have undergone chemotherapy or radiotherapy.
May 28, 2024
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Potential future target for treating primary headache disorders identified
Researchers at Karolinska Institutet have identified an interesting potential future therapeutic target in primary headache disorders. They have found increased amounts of a gene associated with cluster headache, MERTK, and ...
May 28, 2024
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Researchers identify 'degrees of Kevin Bacon' gene in well-connected fruit flies
A team of researchers from the University of Toronto has identified a gene in fruit flies that regulates the types of connections between flies within their "social network."
May 28, 2024
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Genetic cause of rare childhood immune disorders discovered
Scientists have pinpointed genetic changes that can leave children born with little to no immune defense against infection.
May 24, 2024
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Scientists leverage machine learning to decode gene regulation in the developing human brain
In a scientific feat that broadens our knowledge of genetic changes that shape brain development or lead to psychiatric disorders, a team of researchers combined high-throughput experiments and machine learning to analyze ...
May 24, 2024
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