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Immunology news
Medications
You're probably not allergic to penicillin, even if you think you are
If you're one of the millions of Americans who have a penicillin allergy listed on your medical record, research suggests it's highly likely that this label is inaccurate.
1 hour ago
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Oncology & Cancer
Years after his death, late scientist's work could yield new cancer treatments
Some of the final work of a late University of Virginia School of Medicine scientist has opened the door for life-saving new treatments for solid cancer tumors, including breast cancer, lung cancer and melanoma.
2 hours ago
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Key role found for gut epithelial cells in the defense against deadly diarrheal infections
Intestinal epithelial cells line the inner wall of the gut, creating a barrier against dangerous bacteria like enteropathogenic E. coli that seek to attach to and destroy this barrier. Such pathogens pose significant risks ...
7 hours ago
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Researchers suggest B-cells may play role in lung transplant rejection
B-cells infiltrating the lungs may be responsible for one of the most common complications in lung transplantation, which can lead to rejection, according to a study published in the Journal of Clinical Investigation.
8 hours ago
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Researchers make strides in understanding little-known autoimmune myelin-impairing disorder
Blindness and paralysis are often the devastating consequences of little-known disease myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). An Australian research collaboration is looking to change this, ...
5 hours ago
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Gut bacteria metabolite shows promise in fighting inflammatory bowel disease
Gut microbiota or the population of microbial inhabitants in the intestine, plays a key role in digestion and maintenance of overall health. Any disturbance in the gut microbiota can, therefore, have a systemic impact. Intestinal ...
7 hours ago
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Ion channel discovery offers hope for long COVID patients
Researchers from Griffith University's National Center for Neuroimmunology and Emerging Diseases (NCNED) have made a discovery that could bring relief to those struggling with long COVID.
8 hours ago
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Biomolecular atlas for bone marrow offers unprecedented window into blood production
Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have revealed a powerful new bone marrow atlas that will offer the public a first-of-its-kind ...
May 6, 2024
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Study uncovers at least one cause of roadblocks to cancer immunotherapy
T cells—the body's foot soldiers against invaders, ranging from everyday infections to cancers—are integral to many successful immunotherapies. However, a frustrating factor is that immunotherapies do not always work.
May 6, 2024
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Vagus nerve activation of the spleen shows promise to treat infections
One of the main roles of the spleen is to help the body's immune system fight infections. The spleen does this through producing and regulating antibodies—antibody production is negatively affected in various conditions, ...
May 6, 2024
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Study provides a blueprint of tumor-infiltrating B cells with therapeutic implications
In a study published in Science on May 3, researchers unveiled two responding patterns of tumor-infiltrating B cells with therapeutic implications.
May 6, 2024
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Researchers find B cells drive responses of other immune cells, can be modified to prevent multiple sclerosis symptoms
B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), disproving the previous consensus that T cells ...
May 6, 2024
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Researchers generate direct measurement of interaction between immune cells and cancer cells from a patient's biopsy
Researchers at Bar-Ilan University have unveiled a technology that promises to improve cancer treatment decisions based on a patient's biopsy. The pioneering biological research and development measures changes in immune ...
May 6, 2024
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Scientists discover new immunosuppressive mechanism in brain cancer
The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow ...
May 3, 2024
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Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies
Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs destructive immune reactions.
May 3, 2024
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Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets
Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T–cell immunotherapy, where a patient's own immune cells are re-engineered to attack cancer ...
May 3, 2024
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Lymphocytes recruit the immune system to fight most aggressive breast cancer, study confirms
Researchers at the UAB and the Hospital del Mar Research Institute have confirmed that patients with the presence of NK lymphocytes around tumors have a better response to treatment. This confirms the feasibility of using ...
May 3, 2024
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New approach for developing cancer vaccines could make immunotherapies more effective in acute myeloid leukemia
Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft marrow of the bones, typically attacking cells that would otherwise form the key component of the body's immunodefense system, white blood cells.
May 3, 2024
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Drug targeting RNA modifications shows promise for treating neuroblastoma
Neuroblastoma is a common pediatric cancer that originates in developing nerve cells outside the brain. While increasingly intensive treatments have improved the survival of patients with high-risk neuroblastoma, currently ...
May 3, 2024
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Researchers discover how immune B cells hunt down cancer around the body
Scientists have discovered the key features of immune B cells that make them successful at targeting tumors—including when cancer has spread to a different part of the body.
May 2, 2024
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