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Immunology news

Immunology

AI that predicts sequences within antibodies could lead to new therapeutic treatments

A new artificial intelligence model could help design antibodies that better protect the body against viruses and disease. The AI model, known as ImmunoMatch, can predict and identify correct protein pairings within antibodies, ...

Immunology

High stakes of early immune development revealed—and a potential probiotic fix

Antibiotics are powerful treatments that have saved countless lives over the course of decades. New findings from Scripps Research have identified a way to preserve healthy immune development even when infants need antibiotic ...

Diseases, Conditions, Syndromes

How the immune system keeps mucosal fungi in check

The microbiome not only consists of bacteria, but also of fungi. Most of them support human and animal health. However, some fungi also have pathogenic potential. For instance, the yeast Candida albicans can grow in an uncontrolled ...

Oncology & Cancer

Targeting B-cells may boost immunotherapy in liver cancer treatment

Scientists have identified a promising strategy to improve liver cancer immunotherapy: targeting B-cells. While immunotherapy has transformed cancer treatment by activating T-cells—a type of immune cell that fights cancerous ...

Oncology & Cancer

First patient in Arizona treated with new immune cell therapy

A patient with synovial sarcoma, a soft-tissue cancer that usually occurs in the large joints of the arms and legs, is the first in Arizona treated with a new immune cell therapy known as TECELRA at the HonorHealth Research ...

Immunology

CAR T-cell therapy accelerates intestinal healing in aging mice

Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the intestinal epithelium, a single layer of cells that forms the organ's lining. The intestine plays a crucial ...

Arthritis & Rheumatism

SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...

Oncology & Cancer

Bioengineering breathes new life into failed cancer treatment

Many advanced cancers develop resistance to treatment and become highly aggressive, often leaving patients with limited treatment options. In some cancers, including lung, pancreatic and prostate tumors, a key driver of treatment ...

Genetics

Preclinical study identifies genetic misfire in lupus

Cedars-Sinai investigators have identified a "molecular switch" on a gene strongly associated with the autoimmune disease lupus, which appears to propel immune cells into overdrive, attacking and damaging healthy tissues ...

Immunology

AI tool offers deep insight into the immune system

Researchers explore the human immune system by looking at the active components, namely the various genes and cells involved. But there is a broad range of these, and observations necessarily produce vast amounts of data.

Immunology

Physical exercise can 'train' the immune system

In addition to strengthening the muscles, lungs, and heart, regular physical exercise also strengthens the immune system. This finding comes from a study of older adults with a history of endurance training, which involves ...