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Immunology news
Diseases, Conditions, Syndromes
Changing the paradigm on hypermobile Ehlers-Danlos Syndrome: Connective tissues don't tell the whole story
Recent research from the Medical University of South Carolina laboratory of Russell Norris, Ph.D., challenges the notion that hypermobile Ehlers-Danlos Syndrome (hEDS) is an isolated connective tissue disorder, revealing ...
1 hour ago
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Immunology
AI that predicts sequences within antibodies could lead to new therapeutic treatments
A new artificial intelligence model could help design antibodies that better protect the body against viruses and disease. The AI model, known as ImmunoMatch, can predict and identify correct protein pairings within antibodies, ...
3 hours ago
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Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.
10 hours ago
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New antibody design blocks cytomegalovirus from hiding from the immune system
Researchers at Texas Biologics at The University of Texas at Austin, working with scientists internationally, have made an important discovery that could improve treatment of human cytomegalovirus (HCMV), a common but overlooked ...
5 hours ago
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High stakes of early immune development revealed—and a potential probiotic fix
Antibiotics are powerful treatments that have saved countless lives over the course of decades. New findings from Scripps Research have identified a way to preserve healthy immune development even when infants need antibiotic ...
3 hours ago
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Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'
Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.
11 hours ago
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New understanding of T cell receptors may improve cancer immunotherapies
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full ...
11 hours ago
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Doctors provide new hope for pancreatic cancer patients with less invasive radiofrequency ablation
UT Health San Antonio Multispecialty and Research Hospital became the first in South Texas to use an emerging and less-invasive treatment called radiofrequency ablation on a comorbid patient with a pancreatic cancer tumor ...
5 hours ago
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Soil bacteria and fungi emerge as top predictors of childhood allergic disease
The unique blend of fungi and bacteria in a region's soil may be the strongest factor explaining its rates of childhood allergic disease, with certain assemblages of soil critters appearing linked with better health outcomes, ...
7 hours ago
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FDA approves Breyanzi for relapsed, refractory marginal zone lymphoma
The U.S. Food and Drug Administration has approved a new indication for Breyanzi (lisocabtagene maraleucel) for treating adults with marginal zone lymphoma (MZL) who have failed treatment or relapsed after two or more prior ...
22 hours ago
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How the immune system keeps mucosal fungi in check
The microbiome not only consists of bacteria, but also of fungi. Most of them support human and animal health. However, some fungi also have pathogenic potential. For instance, the yeast Candida albicans can grow in an uncontrolled ...
Dec 15, 2025
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Decoding long COVID: Investigators reveal why the body keeps fighting the war
A new study from investigators at Beth Israel Deaconess Medical Center (BIDMC) sheds light on why some people never fully recover from COVID-19.
Dec 15, 2025
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Building a better vaccine: Flu antibodies show expanded role in preventing transmission
Today's influenza vaccines primarily prevent infection in individuals, but new research led by the University of Michigan and the Institut Pasteur suggests that incorporating antibodies generated after infection could lead ...
Dec 15, 2025
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Dramatic drop in HIV-infected immune cells occurs in patient who received cancer treatment
Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at undetectable levels ...
Dec 15, 2025
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Targeting B-cells may boost immunotherapy in liver cancer treatment
Scientists have identified a promising strategy to improve liver cancer immunotherapy: targeting B-cells. While immunotherapy has transformed cancer treatment by activating T-cells—a type of immune cell that fights cancerous ...
Dec 15, 2025
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Large-scale study provides real-world data on rare side effect of cancer immunotherapy
Researchers led by investigators at Mass General Brigham have published valuable information about a rare but serious complication of anti-cancer immunotherapy, providing the first large-scale description of its risk factors ...
Dec 14, 2025
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First patient in Arizona treated with new immune cell therapy
A patient with synovial sarcoma, a soft-tissue cancer that usually occurs in the large joints of the arms and legs, is the first in Arizona treated with a new immune cell therapy known as TECELRA at the HonorHealth Research ...
Dec 14, 2025
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Study shows IL-36 gamma 'armored' CAR T cells can eradicate solid tumors
A laboratory study out of Roswell Park Comprehensive Cancer Center outlines a new way to boost the effectiveness of chimeric antigen receptor (CAR) T-cell therapy in solid-tumor cancers, resulting in their eradication. Led ...
Dec 12, 2025
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Switching immune cells to 'night mode' could limit damage after a heart attack
Researchers at Yale University School of Medicine have identified a way to suppress the daily fluctuations in the activity of key immune cells known as neutrophils.
Dec 12, 2025
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New immunotherapy targets for glioblastoma identified by mapping cell interactions
Glioblastoma is the most common form of brain cancer in adults, and its consequences are usually quick and fatal. After receiving standard-of-care treatment (surgery followed by radiation and chemotherapy), fewer than half ...
Dec 12, 2025
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Mini-tumors combine synthetic and real cells to simulate immune responses
Normally, the immune system recognizes and eliminates abnormal cells. However, cancer cells can develop strategies to evade this control: they block defense mechanisms or send inhibitory signals. In this way, tumors can grow ...
Dec 12, 2025
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Exploring how misguided antibodies cause attacks on the nervous system
A review on autoimmune neurological diseases reveals what occurs in our body when the immune system, by mistake, produces antibodies that target a protein essential for the normal functioning of nerves. The result is hyperexcitability, ...
Dec 12, 2025
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Tricking tumors into marking themselves for destruction with focused ultrasound
USC biomedical engineers have found a way to make a solid tumor paint a target on its own back in order to train the body's immune system to find and destroy it.
Dec 11, 2025
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Farm-living families develop earlier immune maturation against food allergies, study finds
Children who grow up in farming communities have long been known to develop far fewer allergies than their urban peers. A new study from the University of Rochester Medical Center (URMC), offers one possible reason why: their ...
Dec 11, 2025
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CAR T-cell therapy accelerates intestinal healing in aging mice
Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the intestinal epithelium, a single layer of cells that forms the organ's lining. The intestine plays a crucial ...
Dec 11, 2025
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