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Immunology news

Diseases, Conditions, Syndromes

Researchers discover mechanism driving immune perturbations after severe infections

Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated. ...

Diseases, Conditions, Syndromes

COVID-induced immune memory could protect against severe cases of flu, mouse study suggests

More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different ...

Oncology & Cancer

Blood cancers: Expert explains what you need to know

Blood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.

Oncology & Cancer

What is CAR-T cell therapy? Oncologist explains

Roughly 635,000 new cases of lymphoma were diagnosed worldwide, according to the World Cancer Research Fund International's most recent report. Survival rates for aggressive lymphomas have improved significantly thanks to ...

Immunology

Circadian rhythm disruption linked to lung inflammation

In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption ...

HIV & AIDS

'Undetectable' HIV patients could hold key to treatments

A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert.

Immunology

Novel antibodies against Klebsiella pneumoniae identified

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections. Using genetic and functional approaches, the researchers also managed ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Diseases, Conditions, Syndromes

Researcher helps boost immune system memory against influenza

When humans or animals get infected, the body's immune system tries to not only clear the infection but also build up a memory of the pathogen that caused it. So, when the pathogen comes around again for possible reinfection, ...

Genetics

3D genome analysis reveals secrets to antibody diversity

One of the remaining mysteries of immunology is the exact mechanism that B cells use to generate millions of antibodies with different specificities to protect us from the plethora of pathogens in the environment.

Immunology

Study reports discovery of new cell type in thymus

It came as a surprise to Professor David Lo and his graduate student Diana Del Castillo when they were recently consulted by researchers in Israel for their expertise on specialized cells called Microfold cells, or M cells, ...

Diseases, Conditions, Syndromes

Multidrug-resistant bacterium emerging in community settings

New "hypervirulent" strains of the bacterium Klebsiella pneumoniae have emerged in healthy people in community settings, prompting a National Institutes of Health research group to investigate how the human immune system ...

Medical research

Team develops a sugary-sweet new method for biomarker discovery

Everyone loves a sweet treat, even our cells. While we typically think of sugar as a component of our diet that gives us energy, sugars are also very important in guiding the activity of our cells. Sugar molecules can be ...

Oncology & Cancer

Scientists harness 'helper' T cells to treat tumors

Scientists are on the hunt for a unique set of mutations, called "neoantigens," that let the immune system distinguish tumor cells from normal cells. Their goal is to help the immune system react to neoantigens and target ...