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Immunology news
Diseases, Conditions, Syndromes
Immune system proteins involved in severe parasitic disease identified
New insights into the mechanisms that cause more severe cases of schistosomiasis—a disease caused by parasitic worms and second only to malaria in terms of potential harm—have been revealed by researchers at Penn State.
6 hours ago
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Oncology & Cancer
Genomic analysis provides insight into underpinnings of new treatment combination for deadly, Asian-prevalent lymphoma
A multinational research team of clinicians and scientists from South Korea and Singapore has published positive findings from a phase 2 clinical trial for a new combination therapy for an aggressive, Asian-prevalent blood ...
4 hours ago
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Gut microbes release cancer-fighting bile acids that block hormone signals
Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according ...
Apr 15, 2025
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STING protein aids lysosome repair, offering hope for neurodegenerative diseases
The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern ...
Apr 15, 2025
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Engineered T-cells use natural receptors as 'brakes' to target cancer while sparing healthy tissue
A team of researchers has successfully created more effective immune cells that can fight cancer without damaging healthy tissue.
Apr 15, 2025
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A type of immune cell strengthens immunotherapy and prevents tumor relapse in animal models
Scientists have discovered a new immunotherapy strategy that reduces cancer recurrence in mouse experimental models. The study, published in Nature Communications, shows that a specific subtype of immune cell—type I dendritic ...
Apr 15, 2025
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Recently discovered immune cell type could be key to understanding food allergies
The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found in the body's own healthy ...
Apr 14, 2025
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Newly-developed biomimetic materials can improve cancer immunotherapy
Researchers have developed novel lymph-node-inspired hydrogels that significantly enhance the activation, gene expression, and proliferation of CAR T cells.
Apr 14, 2025
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Immune cell 'messengers' could save crumbling bones—new hope for joint pain sufferers
A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse. Researchers have discovered that exosomes ...
Apr 14, 2025
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New immune boost could expand access to cancer immunotherapy
Researchers at Moffitt Cancer Center have found that tapping into the body's own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, ...
Apr 11, 2025
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How one bad protein can affect both immunity and brain development
RIKEN researchers have discovered how a single mutation in one gene can simultaneously result in two symptoms—a severely compromised immune system and problems in brain development. Similar mechanisms may be at work in ...
Apr 11, 2025
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Discovery of new immune response phase upends beliefs about T-cell priming
A team from the Max Planck Research Group for Systems Immunology at the University of Würzburg has identified a previously unknown phase of the immune response. The results, published in Science, challenge long-standing ...
Apr 10, 2025
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Immune protein modification can curb viral replication and heart inflammation
Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.
Apr 10, 2025
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Immune-reactivating antibody therapy shows promise against ovarian cancer in new study
Research has shed light on how a new type of antibody treatment reactivates patients' immune cells to fight ovarian cancer. The research, from the group of Professor Sophia Karagiannis at King's College London, could help ...
Apr 10, 2025
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Discovery of key mechanism could combat lenalidomide resistance in multiple myeloma
A new study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key mechanism behind lenalidomide resistance in multiple myeloma ...
Apr 10, 2025
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Skin injury may bring on food allergies
There's a mysterious connection between our skin and our guts, specifically when it comes to food allergies. For reasons scientists don't fully understand, chronic skin conditions such as eczema are linked to food allergies; ...
Apr 9, 2025
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CAR-M technology: A novel approach to overcome CAR-T limitations in solid tumor treatment
Researchers in South Korea have proposed a novel cancer immunotherapy approach that could complement existing CAR-T (Chimeric Antigen Receptor T-cell) treatments. The work is published in the journal Biomarker Research.
Apr 9, 2025
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Potential Alzheimer's disease therapeutic target identified in brain immune cells
Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer's disease (AD), but its role in the brain was unknown until now.
Apr 9, 2025
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Fiber consumption protects gut from serious bacterial infection, study suggests
A study published in the journal Cell Host & Microbe by Brazilian and American researchers suggests that a diet rich in soluble fiber can protect the intestine against pathogenic bacteria.
Apr 9, 2025
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Menstrual blood is being used to research a range of health conditions, from endometriosis to diabetes and cancer
Menstrual blood has historically been overlooked in research—considered only to be a waste product.
Apr 9, 2025
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How climate change is affecting seasonal allergies
A review published in The Laryngoscope indicates that climate change's effects on pollen seasons and concentrations are contributing to increasing rates of allergic rhinitis, or hay fever.
Apr 9, 2025
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Cancer-fighting implant shows promise in treating melanoma, pancreatic and colorectal tumors
A team of researchers from the Rice Biotech Launch Pad at Rice University has developed an implantable "cytokine factory" that safely triggers potent immune responses against hard-to-treat cancers, including metastatic melanoma, ...
Apr 8, 2025
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Advanced imaging reveals mechanisms that cause autoimmune disease
People who suffer from the autoimmune disease myasthenia gravis experience muscle weakness that can affect any of the muscles we use to blink, smile or even move our body around.
Apr 8, 2025
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Team identifies key regulator blocking immunotherapy, paving the way for a new lung cancer treatment
Immune checkpoint inhibitors, a class of immunotherapies that help immune cells attack cancer more effectively, have revolutionized cancer treatment. However, fewer than 20% of patients respond to these treatments, highlighting ...
Apr 8, 2025
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A gentle approach offers new hope for inflammatory lung diseases
Pulmonary sarcoidosis is a lung disease characterized by granulomas—tiny clumps of immune cells that form in response to inflammation. It's the most inflammatory of the interstitial lung diseases (ILDs), a family of conditions ...
Apr 8, 2025
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